Growth hormone / recovery
CJC-1295 + Ipamorelin Dosage: A Simple Start
How the growth-hormone blend is dosed, and which effect is the reliable one.
The quick version
- A growth-hormone blend run mostly for deeper sleep and recovery.
- The multi-day GH rise is the with-DAC form; the nightly blend uses the short-acting no-DAC version (mod GRF 1-29), which does not.
- Common: about 100 mcg of each at night, empty stomach, 5 days on 2 off.
What it is
CJC-1295 and ipamorelin are usually combined. CJC-1295 nudges your body to release more growth hormone over time. Ipamorelin triggers a clean pulse of it. Together they raise GH without the cortisol spike that older compounds caused. One thing to get straight up front: CJC-1295 comes in two forms, with DAC and without DAC. The no-DAC version is also sold as mod GRF 1-29.
What the research shows
The famous "raises GH and IGF-1 for several days off one shot" result was for CJC-1295 WITH DAC, the long-acting form (Teichman et al., 2006). That multi-day bump does not apply to the no-DAC form. The nightly blend people actually run for sleep uses the short-acting no-DAC version (mod GRF 1-29), which gives a quick pulse and clears fast, so it does not hold GH up for days. Ipamorelin is a selective GH releaser studied mostly in early trials. What is missing is long-term outcome data in healthy adults using the blend for body composition. The hormone moves; the real-world payoff is less proven.
What it felt like
I have run CJC plus ipamorelin in the past, dosed at night. The clearest thing I noticed was deeper sleep inside the first week. Fat loss and recovery were slower and hard to separate from diet and training, so I treat the sleep effect as the dependable part.
Dosing reality
The nightly pattern people share is around 100 mcg of each, before bed, on an empty stomach, 5 days on and 2 off. That schedule is built for the short-acting no-DAC CJC (mod GRF 1-29), not the with-DAC form, so it gives a clean bedtime pulse rather than a days-long GH rise. Eating fat or carbs right before blunts the pulse. These are community numbers, not an approved dose.
The one mistake to avoid
The classic mistake is shooting it right after a meal. Food spikes blood sugar and flattens the GH pulse, so you pay for the vial and get little back. Keep a clear stomach window around the dose.
Bottom line
The blend reliably bumps GH and sleep in the short term. Long-term body composition claims are softer, so keep your expectations there.
Reminder: I am not a doctor and this is not medical advice. It is my own notes and reading of the research. Peptides sit in a legal grey area, research-grade is a real category, and it is on you to verify your own compliance. Talk to a qualified professional before you start anything, especially if you take other medication.
Common questions
What is the CJC-1295 and ipamorelin dosage?
A common pattern is around 100 mcg of each, before bed, on an empty stomach, 5 days on and 2 off. Eating fat or carbs right before blunts the growth hormone pulse. These are community numbers, not an approved dose.
What does CJC-1295 and ipamorelin actually do?
The clearest thing I noticed was deeper sleep inside the first week. The blend reliably bumps growth hormone in the short term, and small studies back that. Long-term fat loss and body composition claims are softer and hard to separate from diet and training.